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Introduction By catalyzing post translational acetylation
2019-05-07
Introduction By catalyzing post-translational acetylation of lysine residues, the histone acetyl transferases (HAT) CREBBP and EP300 moderate the activities of both histone and non-histone proteins. This regulates vital cellular processes such as cell cycling and apoptosis by modulating chromatin s
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El impulso universalista de Sur afect de
2019-05-07
El impulso universalista de Sur afectó de distintas formas su política editorial. En general transitó los marcos de los ideales de Victoria Ocampo, quien además de directora era mecenas del proyecto, y los de José Bianco, que desempeñó por más de 20 años las labores de la secretaría de redacción. La
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br The world population faces various types of
2019-05-07
The world population faces various types of climate-related hazards, and both the frequency and intensity of hazards are projected to increase in the future because of climate change. Since climate change could increase human health risks, many previous studies first estimated future temperatures
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br Ocular surface squamous neoplasia
2019-05-07
Ocular surface squamous neoplasia (OSSN) has emerged as an important manifestation of the HIV epidemic, especially in sub-Saharan Africa. This region has not only gained the unenviable position of having the highest prevalence of OSSN, but patients with HIV tend to present with larger tumours and
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Two other groups subsequently published further
2019-05-07
Two other groups subsequently published further data on iPSCs models of ARVC that have improved our understanding of this disease. Kim et al. developed iPSC models using episomal methods from 2 ARVC patients, as well as with PKP2 mutations . Detailed electrophysiological characterization of mutant a
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The patient underwent surgery on December A cm elastic lobul
2019-05-07
The patient underwent surgery on December 2, 2013. A 13 × 13 cm elastic lobulated yellowish tumor, arising from the upper jejunum with suspected local invasion into the transverse colon and mesentery, was detected intraoperatively. Thus, small bowel segmental resection and left hemicolectomy were pe
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There are several shortcomings to this
2019-05-07
There are several shortcomings to this study that need to be considered. The small size of this series is an obvious shortcoming. Due to the relative rarity of the disease, this problem is not unique to this series and authors of a recent meta-analysis noted the small sample size of other studies as
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Complete resection of the tumor
2019-05-06
Complete resection of the tumor with negative margins at the time of diagnosis appears the most preferred mode of intervention towards favorable prognosis. It is worth mentioning that the germline regorafenib side effects of DICER1 is believed as the genetic cause in the majority of PPB; consequent
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more helpful hints For all analyses a P value was
2019-05-06
For all analyses, a P-value Results A total of 229 patients completed the survey, representing 44% of all ICD patients presenting to the Sunnybrook Health Sciences Center ICD clinic during the study period, of which 78% reported receiving the influenza vaccine. Table 1 summarizes the characteristi
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Quiz algo que podr a unirlos en un futuro
2019-05-06
Quizá algo que podría unirlos en un futuro sea una preocupación generalizada por la violencia, aunque los productos artísticos sobre el tema proceden de generaciones anteriores (por ejemplo, Te diría que fuéramos al río Bravo NSC74859 llorar pero debes saber que ya no hay río ni llanto [2013] de Jor
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Tricot muestra las entra as del Movimiento Mapuche Autonomis
2019-05-06
Tricot muestra las entrañas del Movimiento Mapuche Autonomista con la intención de conducir al lector en la comprensión de la resistencia actual de autoafirmación “ora como pueblo-nación, ora como Identidad Territorial específica”; afirma que el movimiento mapuche “no es un proceso lineal, sino más
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br Discussion There is an important
2019-05-06
Discussion There is an important need for new treatment options for AML in elderly patients. Their frailty imposes limitations upon the aggressiveness of the treatment which can be administered [6,24]. In addition, the poor prognostic disease features often seen in this order LDC000067 mean that
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br Discussion ATS is rare and there are
2019-05-06
Discussion ATS is rare, and there are few reports of pregnant patients with this condition. Subbiah et al. [6] reported a case of pregnancy complicated with ATS in which ventricular ectopy was also decreased during pregnancy. The mechanism underlying the reduction of VA in pregnant patients with
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En M xico el folclor nacionalista de los siglos
2019-05-05
En México, el folclor nacionalista de los siglos xix y xx matizó la tipificada creencia cultural de la “convivencia natural” del mexicano con la muerte para explicar y sobrellevar, incluso de manera socarrona, los estragos económicos y sociales del destino mexicano. Elsa Malvido, en este sentido, en
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Desde ese ngulo es visible c mo la
2019-05-05
Desde ese ángulo es visible cómo la Antigüedad vivía en la medida que era apropiada por los criollos: la gramática latina de Andrés Bello fue novedosa en cuanto explicó la lengua desde el castellano actual (y americano), con la conciencia que éste tenía una estructura distinta. Los símbolos grecorro
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