• br Application of D receptor

  2021-06-08

  

  Application of D1-receptor PET in psychiatric disorders Discussion Compared to other markers of the DA system, only a limited number of studies have investigated D1-R in psychiatric disorders. In schizophrenia, which is the most studied condition with a total of 83 identified unique patients,

• br Discussion The aim of this study was

  2021-06-08

  

  Discussion The aim of this study was to establish staining protocols to enhance the visualization of a dental filling or its remaining in forensic dentistry. Teeth and dental materials resist to most of environmental and disaster conditions, therefore the forensic odontology exam is essential in

• This hydrophobic biphenyl tail gave good binding

  2021-06-08

  

  This hydrophobic biphenyl tail gave good binding affinity for human DHODH enzyme (IC sesamin was found to be the main metabolite in human microsomes and it was 100-fold less active against hDHODH than the ester. In an attempt to identify the specific non-covalent binding interactions which were re

• The data from drug screening in P

  2021-06-08

  

  The data from drug screening in P. berghei (Fig. 3D) provide proof of concept that chemogenomic profiling can be accomplished in P. berghei in the same manner as P. falciparum, in that significant increases in the EC50 ratio were found only for antifolate drugs in the parasite with attenuated TgDHFR

• We aim to apply the same technology to target

  2021-06-08

  

  We aim to apply the same technology to target other collagen-binding proteins using motifs from collagens that are specific for other receptors or matrix components. Previously, we synthesized THP libraries, called Toolkits, composed of an active guest sequence flanked by five GPP host triplets that

• br an anaerobic gram positive spore forming bacterium that

  2021-06-08

  

  , an NGB 2904 gram-positive, spore-forming bacterium that can induce fatal intestinal inflammatory disease, is the most prevalent cause of antibiotic-associated diarrhea and pseudomembranous colitis in nosocomial settings. Two exotoxins, toxin A (TcdA) and toxin B (TcdB), secreted by the bacteriu

• HEK cells stably transfected with

  2021-06-08

  

  HEK-293 BIBR 1532 stably transfected with CysLT1 were stimulated with LTD and internalization was studied by confocal microscopy, FACS or cell-surface ELISA. Cells were co-transfected with wildtype and dominant negative (DN) mutants of arrestin and dynamin. Clathrin-mediated endocytosis was invest

• Steady state mRNA levels of CYP A isoforms

  2021-06-08

  

  Steady-state mRNA levels of CYP3A isoforms were not changed during liver insufficiency. Suppression of these isoforms was observed only at the protein and activity levels, suggesting a nongenomic mechanism of CYP3A isoform downregulation during liver insufficiency. Nonetheless, transcriptional activ

• br Experimental section br Results br Discussion In

  2021-06-08

  

  Experimental section Results Discussion In our previous work (Rashidi et al., 2018) we isolated a novel glucarpidase whose raised caspofungin did not cross-react with the one in clinical use. In principle, therefore, it would be possible to delay the production of antibodies in a patient b

• Abha et al reported Natural

  2021-06-08

  

  Abha et al. reported Natural coumarinolignoids isolated from the seeds of Cleome viscosa consist of a racemic mixture of cleomiscosins A 19, B 20 and C 21 and were screened for anti-inflammatory activity through mol. docking and QSAR studies by using reported in vivo activity of Swiss albino mice. B

• Using characteristic features of ECM proteins and

  2021-06-08

  

  Using characteristic features of ECM proteins and a computational pipeline combining interrogation of protein and gene databases, we previously defined the matrisome as the ensemble of ECM and ECM-associated proteins [[16], [17], [18]]. In mammals, the matrisome represents 4% of the genome, or appr

• The substitution of serine by an

  2021-06-08

  

  The substitution of serine 185 by an alanine led to an increase of EGF-R stabilization along with a better binding of PRK1, a RhoB effector described to be involved in EGF-R intracellular traffic. Overall these data indicated that the phosphate group on serine 185 impaired its binding to the effecto

• RK-33 receptor The oxidation of the lipid

  2021-06-08

  

  The oxidation of the lipid fraction of meat is an extremely complex process because of the high sensitivity of oxidation products to decomposition, their reactions with other components, the complex effect of catalysts and the presence of antioxidants. These changes are the main cause of limited she

• Theoretically the expression profile of GluCl

  2021-06-08

  

  Theoretically, the expression profile of GluCl variants was related to their physiological roles. It was reported that all the three variants (GluCl A, GluCl B, GluCl C) were highly expressed in head tissue of L. striatellus and M. domestica, and the expression level of GluCl A was significantly hig

• We hypothesize that both IGF dependent

  2021-06-08

  

  We hypothesize that both IGF-1-dependent kinase activation and locally synthesized neuroestrogens interactively regulate estrogen receptor activity in neuronal 2-Deoxycytidine in the absence of exogenously applied estradiol. The Neuro-2A cell line was chosen as the model system for these studies be

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