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In this report we characterized MRJP
2022-07-06

In this report, we characterized MRJP-containing NADP/NADPH Quantitation Colorimetric Kit sale and other (glyco)proteins from honey. Honey glycoproteins demonstrated potent anti-C. elegans activity. It has been reported that molecules that kill C. elegans are likely to be toxic to parasitic nematode
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br Introduction The generic antifibrinolytic drug tranexamic
2022-07-06

Introduction The generic antifibrinolytic drug tranexamic Tubacin receptor (TXA) inhibits the protein-protein interaction between plasminogen and fibrin [9]. TXA is frequently used to reduce bleeding in various hemorrhagic conditions, such as during surgical procedures in the heart [19]. However
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In contrast to short term effects long term
2022-07-06

In contrast to short-term effects, long-term exposure of beta cells to FFAs impairs insulin secretion and triggers apoptosis [13]. The deleterious effects of FFAs have been linked to altered glucose/fatty Tigecycline oxidation cycle [13], decreased NADPH content [14], endoplasmic reticulum (ER) str
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br Materials and methods br Results br
2022-07-06

Materials and methods Results Discussion Here, we investigated the inhibitory effects and associated mechanisms of phloroglucinol on α-glucosidase. Our results showed that phloroglucinol reversibly inhibited α-glucosidase in a dose-dependent manner (Fig. 1), with the double-reciprocal plot
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br Experimental Procedures br Acknowledgments This work was
2022-07-06

Experimental Procedures Acknowledgments This work was supported by NIH/National Human Genome Research Institute (NHGRI) R00 HG006922 and NIH/NHGRI R01 HG008974 (to J.G.), the Huntsman Cancer Institute, and the Women’s Cancers Disease-Oriented Team at the Huntsman Cancer Institute. Research rep
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The regulation of casein expression during
2022-07-06

The regulation of casein expression during lactation is a complex process involving a coordinated response at several levels. A variety of hormones are known to play roles in lactogenesis, such as prolactin (PRL), insulin, and hydrocortisone, and there is now increasing evidence that growth factors,
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Conclusion By generating high quality hypocotyl
2022-07-05

Conclusion By generating high-quality hypocotyl transcriptomes of a jute hypocotyl-defect mutant and its wild-type comprising the largest number of annotated unigenes (39,076), we identified a complete array of structurally and functionally diverse β-galactosidases. Our proposed domain-centric clas
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In the thoracic spinal cord
2022-07-05

In the thoracic spinal cord, neither glacial acetic Phosphate Colorimetric Assay Kit nor HBO2 had an effect on nNOS expression or expression of the phosphorylated β3 subunit of the GABAA receptor. This result was not unexpected due to the preponderance of nociceptive signaling in the lumbar versus
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br Materials and methods br Results and discussion In order
2022-07-05

Materials and methods Results and discussion In order to identify genes required for photoautotrophic growth, we screened a random insertion mutant library of Synechocystis 6803 and obtained many mutants with impaired photoautotrophic growth. About 6000 random insertion colonies of the mutant
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Enhancer of Zeste Homolog EZH is a core component of
2022-07-05

Enhancer of Zeste Homolog 2 (EZH2) is a core component of the Polycomb Repressive Complex2 (PRC2) which also includes SUZ12 and EED. PRC2 represses gene transcription through trimethylation of Lys27 of histone H3 (H3K27), and contribute to the maintenance of cell identity, DMAP regulation and oncog
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microRNAs miRNAs of approximately nucleotides play vital rol
2022-07-04

microRNAs (miRNAs) of approximately 22 nucleotides play vital roles in cancer development and progression by regulating translational repression or decay of target messenger RNAs (mRNAs) through their binding to the 3′-untranslated regions (3′-UTRs) of target mRNAs with imprecise or precise compleme
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As evidenced by SARs and
2022-07-04

As evidenced by SARs and crystallographic data, HO-1 has at least three main crucial regions for inhibitor binding. The most crucial area, the so-called eastern region, is able to allocate the azole ring that represents the first anchoring point by establishing a coordination binding to the heme fer
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It has been reported that CD glioma
2022-07-04

It has been reported that CD133+ glioma stem Cryptotanshinone receptor are resistant to temozolomide (TMZ) therapy [155]. Dose dependent TMZ treatment of CD133+ cells enhanced activities of the Notch and SHh pathways [156]. Moreover, 500 μmol/L TMZ induced a significant upregulation of Gli1, HES1 a
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Introduction Inorganic arsenic InAs species such as
2022-07-04

Introduction Inorganic arsenic (InAs) species such as arsenite (AsIII) and arsenate (AsV) are present in groundwater. Arsenic contaminated drinking water is a global public health issue because of its natural prevalence and toxicity. Long exposure to arsenic results in chronic effect in humans, inc
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Importantly lactate and H exert some of their biological eff
2022-07-04

Importantly, lactate and H+ exert some of their biological effects independently of each other, though sometimes through redundant pathways leading to a same biological effect, as for angiogenesis. In other cases, they can have antagonist effects: lactate was shown to stimulate extracellular matrix
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