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The safety profile of CFZ used
2018-10-23
The safety profile of CFZ used as a single agent for the treatment of relapsed and/or refractory MM was analyzed in a total of 526 patients enrolled in the four phase II clinical trials based on which the U.S. FDA approval was granted. The most severe side effects reported include: sudden death (wit
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The present study by Rouers and coworkers
2018-10-23
The present study by Rouers and coworkers found that within EC there was a much higher frequency of HIV Env-specific memory B cell responders compared to patients that have been rendered aviremic through the use of cART (). Remarkably, this was despite the fact that members of the EC cohort were inf
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Prior experimental studies have demonstrated that genetic an
2018-10-23
Prior experimental studies have demonstrated that genetic and pharmacological inhibition of the proteasome in the cardiomyocyte compartment exacerbates acute myocardial ischemia/reperfusion injury and the maladaptive cardiac remodeling and ep4 antagonist failure induced by acute pressure overload ()
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Value of the data br Data experimental design materials
2018-10-23
Value of the data Data, experimental design, materials and methods Acknowledgments This work was financially supported by the grant sponsors: Shenzhen Municipal Committee of Science and Technology Innovation (Grant number: JC201105190969A) and the National Public Sector (AQSIQ) Special Funds
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br Data experimental design materials and methods br Data
2018-10-23
Data, experimental design, materials and methods Data, experimental design, materials and methods Acknowledgments This work was supported by the Molecular and Cell Biology Research Center (MCBRC), Mazandaran University of Medical Sciences, Iran (grant number 1658); and the Iran National Sci
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br Acknowledgments We thank Sofie Vande Casteele for the ass
2018-10-23
Acknowledgments We thank Sofie Vande Casteele for the assistance with the maintenance of our Waters Premier LC–MS, the platform applied for the development, and optimization of the protocol. We thank Niklaas Colaert for the support with the Rover software and Kristof De Beuf from the FIRE Statist
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Ultrasonic waves propagate in materials at
2018-10-22
Ultrasonic waves propagate in materials at a constant velocity. This behavior allows them to be used for non-destructive investigation purposes. Different studies were conducted to determine the hardness of various materials using the velocity variations of ultrasonic wave. Tariq et al. [15] correla
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Temperature distribution is localised in the
2018-10-22
Temperature distribution is localised in the thin cut-edge surface layer and the b-raf inhibitors coupling at the workpiece surface is important in terms of determining the cut-edge quality. Using high power intensity can therefore result in the beam being absorbed by the workpiece material, which
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orthopox J venes precariedad y reordenamiento geopol tico
2018-10-22
Jóvenes, precariedad y reordenamiento geopolítico Es innegable que las formas en las que se ha configurado y se reconfigura el concepto de trabajo en las sociedades actuales, mayoritariamente capitalistas, tiene gran influencia en la manera en que se construye la subjetividad contemporánea. Esto ti
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br A modo de conclusi n Como hemos analizado el
2018-10-22
A modo de conclusión Como hemos analizado, el espacio en las obras de Diamela Eltit es el escenario de luchas de poder que se disputan un territorio para instalar tecnologías para la normalización de los individuos. Por esto, los personajes se resisten histamine inhibitors esas técnicas fracturan
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dihydrofolate reductase inhibitor Analogously to the export
2018-10-22
Analogously to the export, inbound tourism can stimulate economic growth in numerous ways. For instance, first, tourism significantly contributes to foreign exchange reserves which help in bringing new technologies for production process (McKinnon, 1964). Secondly, tourism stimulates investments in
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i was reading this The Crystal Palace was probably the first
2018-10-22
The Crystal Palace was probably the first exhibition hall of functionalism that utilized the technological advancement of i was reading this iron and glass for its building materials and light structural frames for its construction. Banham (1974) praised Paxton\'s Crystal Palace for its functional
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Investigating the logic of collective housing under modernis
2018-10-22
Investigating the logic of collective housing under modernism, which was derived from Europe, is necessary to examine the principles of planning and the influx of collective housing to South Korea. In this way, we can deduce the logical influence and background of how the linear type apartment becam
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Considering the importance of design thinking in the
2018-10-22
Considering the importance of design thinking in the design process (Dorst, 2011) and in design studio (Oxman, 2004), researchers have emphasized the necessity to understand the cognitive processes of the human mind to enhance the understanding of design thinking (Oxman, 1996, Nguyen and Zeng, 2012)
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The Advanced Trauma Life Support
2018-10-22
The Advanced Trauma Life Support (ATLS) course was developed by the American College of Surgeons, Committee on Trauma in the 1980s. The ATLS course provides participants with a safe and reliable method for the immediate treatment of injured patients. The scope of the ATLS course includes rapid asses
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