• In contrast to the normal cells the requirement for

  2018-10-24

  

  In contrast to the normal cells, the requirement for cell:cell contacts to promote survival was removed in the H7 and H14 adapted cells, implying the loss of niche dependence, as has also been reported elsewhere (Werbowetski-Ogilvie et al., 2009). Consequently, the functional significance of the obs

• The expression of neurotrophic or angiogenic proteins by gra

  2018-10-24

  

  The expression of neurotrophic or angiogenic proteins by grafted neural xanthine oxidase benefits the two types of transplanted progenitors in the infarct core. First, BDNF, which is known to be neuroprotective (Louhivuori et al., 2011), may ensure the survival of newly formed neurons during the fir

• The concept of neoblast specialization at wounds

  2018-10-24

  

  The concept of neoblast specialization at wounds is important in understanding planarian regeneration and opens many avenues for future inquiry. For example, how is the neoblast response tailored to the identity of missing tissues? Do specialized neoblasts amplify their population, or do specialized

• Unlike these previous methods the S reprogramming system gen

  2018-10-24

  

  Unlike these previous methods, the 3S reprogramming system generates partially reprogrammed iPSCs in a reproducible and predictable manner by regulating the amount of KLF4. These potassium channel blocker resume reprogramming upon increased KLF4 expression and therefore are not aberrantly reprogram

• The aim of this study was to determine the

  2018-10-24

  

  The aim of this study was to determine the growth rate of human dental pulp stem dhpg (hDPSCs) under physiological oxygen tension (3%), and to investigate the cell signaling pathways underlying decreased stem cell proliferation during routine culture under ambient oxygen tension (21%). We show that

• Expression profiles from tumor tissue and derived cell lines

  2018-10-24

  

  Expression profiles from tumor tissue and derived cell lines are extremely different, thus the current transcriptomic signature for GBM subtyping may not apply in vitro. Using our precursor state signature, we were able to identify an association with the proneural and mesenchymal subtypes. Interest

• An increase in the PGC number caused by dnd

  2018-10-24

  

  An increase in the PGC number caused by dnd RNA injection does not exceed 3-fold, even if a high level of Dnd expression occurs in many cells. It is likely that an additional factor essential for PGC specification exists in medaka, which shows expression and PGC-specifying activity similar to dnd bu

• The activation of Notch has

  2018-10-24

  

  The activation of Notch1 has been found to contribute to the invasion and metastasis of cancer via the EMT. In addition, Saad et al. (2010) showed that the overexpression of NOTCH1 induces the expression of SNAIL. In the present study, after GSI treatment the expression of NOTCH1, SNAIL1, and SNAIL2

• We speculated that MEKi might decrease DNA methylation

  2018-10-24

  

  We speculated that MEKi might decrease DNA methylation levels through the downregulation of the DNMT3 family. MEKi significantly diminished global DNA methylation levels and, surprisingly, was sufficient to induce high 5hmC levels. Because the TET family of dioxygenases that catalyze the conversion

• br This result is not

  2018-10-24

  

  This result is not unexpected, as the Crocco Eq. (3) is equivalent to a canonical system. A similar result is obtained when splitting series in the case of the Blasius equation: which is not connected to any variational problems. Furthermore, let y be and the split linear system takes the for

• br Numerical computations We present here the calculation da

  2018-10-24

  

  Numerical computations We present here the calculation data obtained for the structure prepared from ytterbium (Yb, eφ = 3.1 eV) and carbon (C, eφ = 4.7 eV) layers. Calculations necessary to optimize the layered field emitters and determine their emission characteristics have been carried out us

• Fiber separation in the reinforcing yarns and damages in

  2018-10-24

  

  Fiber separation in the reinforcing yarns and damages in the yarn matrix may occur during the deformation of flexible woven composite materials due to debonding between the reinforcing fibers and the adhesive. These processes can be described as \'smeared cracks’ [18-21]. This description is based o

• whose general solution has the form br

  2018-10-24

  

  whose general solution has the form Let us consider a rectangular plate with the relative dimensions where γ=a/b is the aspect ratio of the plate. If we impose the requirement that deflection function (2) of the plate must satisfy the homogenous boundary conditions at the edges y=0 and y=1, the

• The full spin of the

  2018-10-24

  

  The full spin of the Fe2+ ion can be equal to 4/2 or 0 depending on whether external molecular complex is adjoined to it. Let us note that this property determines the possibility of the oxygen transport by the red blood ap-1 in living organisms. It is shown in this paper that, in the case of sill

• Literacy is a fundamental resource highly correlated with

  2018-10-24

  

  Literacy is a fundamental resource highly correlated with educational attainment. Broadly, literacy has been defined as using printed and written information to function in society, to achieve one’s goals, and to develop one’s knowledge and potential. Literacy enables individuals to gain knowledge a

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