• Dysregulation or mutations of catenin are widespread in

  2018-11-03

  

  Dysregulation or mutations of β-catenin are widespread in GIC, and altered β-catenin plays fundamental roles in GIC initiation and progression (Basu et al., 2016; Oguma et al., 2008; Vogelstein et al., 2013). By interacting with β-catenin, ASF1A thus exhibits multiple oncogenic activities, as docume

• br Bioinformatic analyses Standard bioinformatics analyses a

  2018-11-03

  

  Bioinformatic analyses Standard bioinformatics analyses about this work were reported by Yang et al. [1]. We calculated gene expression values by the read/fragments per kilobase of consistency per million fragments mapped (RPKM/FPKM) and the False Discovery Rate (FDR). Genes with an FPKM ratio ≥2

• Brain imaging and genetic data alone

  2018-11-03

  

  Brain imaging (and genetic) data alone are insufficient for tracking trajectories in small molecule library screening development. A significant time commitment must be made to the assessment of cognition and mental health. In the Saguenay Youth Study, for example, we have spent ∼8 h of the partici

• br Methods br Results br Discussion br Conclusion br

  2018-11-03

  

  Methods Results Discussion Conclusion Conflicts of interest Acknowledgements Introduction Cross-sectional and longitudinal structural magnetic resonance imaging (MRI) studies have demonstrated that the human brain undergoes significant development during adolescence (Gogtay et a

• We are grateful to Elsevier and the Editors of

  2018-11-03

  

  We are grateful to Elsevier and the Editors of for devoting this trifluoperazine special issue to the inaugural meeting of , which took place on September 19–21, 2013 in Pittsburgh, Pennsylvania. The concept and motivation for the Flux Congress emerged from the recognition that our burgeoning disci

• br Conclusion In summary our study suggests

  2018-11-03

  

  Conclusion In summary, our study suggests that activation in both the default network and fronto-parietal network during spatial working memory contributes to individual differences in behavioral performance even at a young age. In a group of youth 9–12 years of age, across participant difference

• Our study had a number of

  2018-11-03

  

  Our study had a number of limitations that should be addressed in future research. First, the study utilized a cross-sectional design to examine a developmental question. A longitudinal design would better control for individual differences in the sample. Second, it is possible that the task, partic

• Why was the model able to

  2018-11-03

  

  Why was the model able to capture these qualitative effects? That is, what was the mechanistic account of the empirical data? In the model, there is experimental control over the constraints that shape development. We can therefore plot predictive power of these constraints across development, split

• NMS-873 Currently much developmental neuroimaging work on co

  2018-11-03

  

  Currently, much developmental neuroimaging work on cognitive control has been done using working memory tasks. A recent met-analysis of this literature documented bilateral dlPFC (BA6) activity to significantly increase with age during working memory (Andre et al., 2016). Moreover, from a theoretica

• br Acknowledgements The research is funded by Azienda Unit S

  2018-11-03

  

  Acknowledgements The research is funded by Azienda Unità Sanitaria Locale (AUSL) of Bologna. (Fondi Sanzioni D.Lgs. 758/2011). The authors are grateful for this support. Data Data presented here deal with monitoring of selected heavy metals including Cd, Pb and As in Aghili plain, Khuzestan p

• The stratum corneum of lower layers has a neutral pH

  2018-11-03

  

  The stratum corneum of lower layers has a neutral-pH microenvironment, in which LEKTI is bound to KLKs immediately after release from granular cells. Therefore, KLKs are kept in an inactivated condition. To activate KLKs, acidification of the microenvironment is required, because LEKTI is released f

• Introduction Psoriasis is a common chronic immune mediated

  2018-11-03

  

  Introduction Psoriasis is a common, chronic, immune-mediated disorder of the skin that affects 2–3% of the population worldwide. In Asians, the incidence of psoriasis vulgaris is estimated at 0.05–0.3%. Patients present with a broad range of clinical manifestations with symptoms that vary in severi

• Previous studies showed that parotid sublingual and submandi

  2018-11-03

  

  Previous studies showed that parotid, sublingual and submandibular glands produce and release irisin into saliva. Salivary irisin levels were found to be elevated in patients with Prader–Willi syndrome, whereas they Bioactive Compound Library were found to be reduced and correlated with serum irisi

• glycine transporter br Discussion EMN is a rare phenomenon

  2018-11-03

  

  Discussion EMN is a rare phenomenon in which hundreds of melanocytic nevi appear suddenly. The lesions of EMN can include banal nevi, blue nevi, and Spitz nevi. EMN may arise in the setting of blistering skin disease, immunosuppression, cytokine administration, biological agent administration, ch

• br Correlation Hardness and ultrasonic wave

  2018-11-03

  

  Correlation Hardness and ultrasonic wave velocity measurements are performed before and after each annealing stage. Their variation in initial condition are investigated in terms of annealing temperature, and then the variations of hardness and ultrasonic wave velocity are correlated for each ste

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