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Intrinsic factors that induce neurogenesis include neurotrop
2018-11-12
Intrinsic factors that induce neurogenesis include neurotrophins and neuropeptides, which are released by neuronal activity. Two specific factors, neuropeptide VGF (non-acronymic) and Brain-Derived Neurotrophic Factor (BDNF) have received attention in the context of their contribution to either prol
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br Materials and methods br Results br Discussion In these
2018-11-12
Materials and methods Results Discussion In these experiments, we sought to determine the influence of gravitational mechanical unloading on the regenerative ability of bone marrow progenitors and specifically hypothesized that exposure to microgravity may alter the differentiation of bone
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The following are the supplementary related to
2018-11-12
The following are the supplementary related to this article. Acknowledgment We would like to thank for the financial support by the ALF Research Grant, Stockholm County Council; Chinese Scholarship Council, PR China; Craig Hospital Foundation, CO, USA; Magnus Bergvall Foundation, Svenska Läkarsä
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Interferons are a diverse family of
2018-11-12
Interferons are a diverse family of cytokines which possess antiviral and immunomodulatory properties (Isaacs and Lindenmann, 1957; Stark et al., 1998; Theofilopoulos et al., 2005). These specialized proteins are produced by cells in response to viral infection. Cellular sensors such as retinoic HBT
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Transplantation of c kit RCSC
2018-11-12
Transplantation of c-kit+ RCSC shifted the balance between pro- and anti-angiogenic proteins in the pressure-overloaded LV myocardium towards pro-angiogenic mediators and the myocardium of transplanted mice showed an increased density of endothelial (CD31+) cells. In contrast, GFP+ cardiomyocytes we
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prostanoid receptors Here we demonstrate that postnatal pitu
2018-11-09
Here we demonstrate that postnatal pituitary SOX2+ stem prostanoid receptors are derived from the embryonic RP and that the Notch signaling pathway is essential for their proliferation, maintenance, and postnatal pituitary expansion. Furthermore, we present evidence that SOX2+ stem cells make a sig
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br Results br Discussion Different
2018-11-09
Results Discussion Different routes of reprogramming have been described even when starting with MEFs but these are restricted to late stages of reprogramming and have been demonstrated with different combinations of reprogramming factors (Parchem et al., 2014). Interestingly, recent reports a
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A perceptron network that had
2018-11-09
A perceptron network that had previously proved to be the most sensitive to new complementary data about the model was used in the experiments. The number of THZ531 in the network was chosen to equal 20 (n = 20); the data used was on the correspondence between the sought-for solution and the approx
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The comparison of the modeled and the
2018-11-09
The comparison of the modeled and the experimental images (Fig. 6) showed that the experimental images for small QDs for g = 220 (see Fig. 6 (d)) match the simulations in moiré period and the number of moiré fringes with a 6% lattice mismatch (Fig. 6 (a)). This means that small QDs consist of pure i
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Suggesting it would be worthwhile to
2018-11-09
Suggesting it would be worthwhile to extend the time frame of analyses are several salient temporal changes: (a) declines in the infant mortality rate and changes in its recognized determinants (e.g., socially patterned declines in smoking during pregnancy and increases in gestational diabetes) (SAC
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pp1 In sum understanding more precisely how mindsets relate
2018-11-09
In sum, understanding more precisely how mindsets relate to the processes that occur immediately after mistakes in this pp1 younger age range may open novel avenues for research and intervention to improve resilience. Thus, in the current study, school-age children performed a developmentally appro
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The findings from this study cannot necessarily be extrapola
2018-11-09
The findings from this study cannot necessarily be extrapolated to other children at risk of stunting, since there may be dietary, cultural, and environmental factors that differ from the setting in rural Malawi. Serum metabolite concentrations may change over time. However, studies in adults show t
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Finally in the context of
2018-11-09
Finally, in the context of this adipose specific FABP4 transgenic (over expression) mouse model phenotype, it is essential to discuss the caveats of this animal model. In the last five years several reviews have highlighted the advantages and disadvantages of the different promoters (for example FAB
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DNA methylation is a mechanism involved in the control
2018-11-09
DNA methylation is a mechanism involved in the control of tissue-specific gene expression (Jones, 2012). DNA hypermethylation of CpG dinucleotides acts as an inhibitor of transcription while hypomethylation is associated with increased gene expression. Differences in DNA methylation patterns between
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Autophagy also plays a role
2018-11-09
Autophagy also plays a role in response to treatment. An extensive literature suggests that autophagy can protect cancer cells against commonly used cancer therapies including a wide array of different drugs and radiation (Thorburn et al., 2014; Rebecca and Amaravadi, 2015). Such studies are the bas
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