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bet inhibitor To verify this hypothesis OGD was adopted
2019-04-19
To verify this hypothesis, OGD was adopted to mimic cerebral ischemic injury in rat cortical astrocyte-neuron co-cultures in the present study. This co-cultures system allows us to manipulate astrocytes and neurons respectively, and simultaneously allows the two kinds of cells to exchange soluble me
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The nutrition support team NST estimated his nutritional sta
2019-04-19
The nutrition support team (NST) estimated his nutritional status and began the intervention. An inadequate calorie intake (due to swallowing difficulty) induced malnutrition in the patient; his bodyweight (BW) loss exceeded 8% in 3 months, his body mass index (BMI) was 21 kg/m2, triceps skinfold th
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Bisphosphonates are a well established standard
2019-04-19
Bisphosphonates are a well-established, standard-of care treatment option to reduce the frequency and severity and time of onset of the skeletal related events (SREs) in patients with bone metastases due to either solid tumours or multiple myeloma [21–33]. From many years, BPs have been incorporated
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br Case report We report
2019-04-19
Case report We report on a 28-year-old male without any past medical history. After a minor work accident (professional mechanic) he noticed significant pain in his left knee. The pain increased over time and a radiograph was taken. It showed minor bone resorption at the neck of the left proximal
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Primarily the management of GCTs has been curettage followed
2019-04-19
Primarily, the management of GCTs has been curettage followed by filling with bone cement [7,19]. However this has been associated with high recurrence rates. Additional treatment with adjuvants is often employed to reduce this recurrence. These adjuvants may include zinc chloride, bisphosphonates,
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Effect of atorvastatin in modulation and protection of cardi
2019-04-19
Effect of atorvastatin in modulation and protection of cardiomyocyte ischemia and inflammatory phenomena (identified as a decline in perioperative CRP, hs-cTnT, and CPK-MB levels) [15,25–27] was not confirmed in the PROFACE trial. Because of no significant differences in the clinical preoperative or
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br Conflicts of interest br Acknowledgment This work was
2019-04-19
Conflicts of interest Acknowledgment This work was supported, in part, by a grant from the Experimental Research Center ELPEN (Y97/2-12-2013). The funding source had no involvement in the study design, in the collection, analysis and interpretation of data, in the writing of the report, and in
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Pilsicainide might increase hERG proteins via facilitating
2019-04-19
Pilsicainide might increase hERG proteins via facilitating the transcription of hERG from DNA to RNA or the translation of hERG RNA into hERG protein. Qualitative RT-PCR demonstrated the absence of an increase in hERG mRNA expression levels after pilsicainide treatment (Supplemental Fig. S2), indic
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This study provides an innovative
2019-04-19
This study provides an innovative model to harness national household survey data to quantify the effects of the various malaria control interventions. The model accounts for the spatial dependence in parasitaemia as a consequence of the heterogeneous distribution of malaria transmission and its dri
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Estimates of life expectancy are of obvious importance to pe
2019-04-19
Estimates of life expectancy are of obvious importance to people with HIV-1, and are essential to monitor and predict the progress of the HIV/AIDS epidemic and to plan health services. The Rwandan study reported by Sabin Nsanzimana and colleagues in is the first from sub-Saharan Africa to focus on
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En la obra de Cuadra
2019-04-19
En la obra de Cuadra, una familia campesina confronta trágicamente la guerra civil entre conservadores y liberales. Víctimas pasivas de las élites y no actores políticos, estos campesinos ven cómo los principios familiares tradicionales y del minifundio son desarticulados por la guerra y el abuso de
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Acerca do cinema cubano Sol Aymara em artigo denominado
2019-04-18
Acerca do cinema cubano, Sol Aymara, em artigo denominado Breve mirada al cine cubano, sustentou que houve um desenvolvimento significativo da cinematografia do país em razão do apoio decisivo da Revolução e do próprio Fidel Castro, que mostrou interesse particular em desenvolvê-lo, contribuindo par
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br POR QU UNA PO TICA DEL EXILIO A
2019-04-18
¿POR QUÉ UNA POÉTICA DEL EXILIO? A lo largo de nuestra investigación hemos seleccionado diversos autores y sus perspectivas que nos permiten analizar el objeto de estudio. Existe, por una parte, una dificultad por reconocer una problemática que atienda las necesidades de las producciones intelect
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El impulso universalista de Sur afect de distintas formas
2019-04-18
El impulso universalista de Sur afectó de distintas formas su política editorial. En general transitó los marcos de los ideales de Victoria Ocampo, quien además de directora era mecenas del proyecto, y los de José Bianco, que desempeñó por más de 20 años las labores de la secretaría de redacción. L
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Azacitidine was administered at a dose of mg
2019-04-18
Azacitidine was administered at a dose of 75mg/m2/daily subcutaneously for 7 consecutive days every 28days. Transient neutropenia was observed until the seventh retinoid x receptor of the azacitidine treatment was completed. A gradual increase in his blood cell count was noted and the patient event
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