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Pilsicainide might increase hERG proteins via facilitating
2019-04-19
Pilsicainide might increase hERG proteins via facilitating the transcription of hERG from DNA to RNA or the translation of hERG RNA into hERG protein. Qualitative RT-PCR demonstrated the absence of an increase in hERG mRNA expression levels after pilsicainide treatment (Supplemental Fig. S2), indic
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This study provides an innovative
2019-04-19
This study provides an innovative model to harness national household survey data to quantify the effects of the various malaria control interventions. The model accounts for the spatial dependence in parasitaemia as a consequence of the heterogeneous distribution of malaria transmission and its dri
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Estimates of life expectancy are of obvious importance to pe
2019-04-19
Estimates of life expectancy are of obvious importance to people with HIV-1, and are essential to monitor and predict the progress of the HIV/AIDS epidemic and to plan health services. The Rwandan study reported by Sabin Nsanzimana and colleagues in is the first from sub-Saharan Africa to focus on
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En la obra de Cuadra
2019-04-19
En la obra de Cuadra, una familia campesina confronta trágicamente la guerra civil entre conservadores y liberales. Víctimas pasivas de las élites y no actores políticos, estos campesinos ven cómo los principios familiares tradicionales y del minifundio son desarticulados por la guerra y el abuso de
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Acerca do cinema cubano Sol Aymara em artigo denominado
2019-04-18
Acerca do cinema cubano, Sol Aymara, em artigo denominado Breve mirada al cine cubano, sustentou que houve um desenvolvimento significativo da cinematografia do país em razão do apoio decisivo da Revolução e do próprio Fidel Castro, que mostrou interesse particular em desenvolvê-lo, contribuindo par
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br POR QU UNA PO TICA DEL EXILIO A
2019-04-18
¿POR QUÉ UNA POÉTICA DEL EXILIO? A lo largo de nuestra investigación hemos seleccionado diversos autores y sus perspectivas que nos permiten analizar el objeto de estudio. Existe, por una parte, una dificultad por reconocer una problemática que atienda las necesidades de las producciones intelect
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El impulso universalista de Sur afect de distintas formas
2019-04-18
El impulso universalista de Sur afectó de distintas formas su política editorial. En general transitó los marcos de los ideales de Victoria Ocampo, quien además de directora era mecenas del proyecto, y los de José Bianco, que desempeñó por más de 20 años las labores de la secretaría de redacción. L
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Azacitidine was administered at a dose of mg
2019-04-18
Azacitidine was administered at a dose of 75mg/m2/daily subcutaneously for 7 consecutive days every 28days. Transient neutropenia was observed until the seventh retinoid x receptor of the azacitidine treatment was completed. A gradual increase in his blood cell count was noted and the patient event
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br Material and methods br Results
2019-04-18
Material and methods Results Discussion Activated microglia has been shown to be a hallmark of central nervous system (CNS) inflammation, which further mediating the subsequent neuronal apoptosis [1], [2], [3], [27], [28]. However, the underlying molecular mechanisms have not been well eluc
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An incisional biopsy was undertaken Peri
2019-04-18
An incisional biopsy was undertaken. Peri-operative examination of the lesion revealed an expansile tumor mass brownish in color with focal whitish areas (Fig. 3). The lesion could be delineated from the surrounding cortical bone, and surrounding soft tissues. Histopathologically the biopsy material
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Partamos primero de la v ctima sacrificial Fernando Valle De
2019-04-18
Partamos primero de la víctima sacrificial: Fernando Valle. Desde su juventud, Fernando es aislado de la sociedad. Su familia lo rechaza, como explica al médico-narrador (120). Una víctima “sacrificable”, según Girard, tiene que ser alguien diferenciado de la sociedad; las víctimas son seres margina
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Apicidin manufacturer The gallstone Lith gene map has been u
2019-04-18
The gallstone (Lith) gene map has been updated, which lists all known genetic loci that confer gallstone susceptibility, as well as candidate genes in inbred strains of mice. Understanding molecular genetics of gallstone disease in mice will push for the identification of human Lith genes. In additi
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br Discussion Clinically HES may be separated into two subgr
2019-04-18
Discussion Clinically, HES may be separated into two subgroups: HES with, and HES without gene abnormality such as PDGFRA, PDGFRB, or FGFR1. The standard therapy of HES without gene abnormality is steroid; by contrast, the first-line therapy of HES with gene abnormality is imatinib. Although in-
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The benign exostoses in TRPS
2019-04-18
The benign exostoses in TRPS have a recognized malignant potential which have been shown to develop into chondrosarcomas [4,13]. Both our index case and his mother demonstrated de novo high grade osteosarcoma. To our knowledge, this occurrence has not been described anywhere within the literature.
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Regarding patients with a lower annual
2019-04-18
Regarding patients with a lower annual risk of thromboembolism ( Management of direct acting oral anticoagulants during pacemaker insertion There are less data available regarding management of DOACs peri-procedurally. The general principle is that PM/ICD implantation is considered a low bleeding
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